Popa I, Pin D, Remoue N et al. Analysis of epidermal lipids in normal and atopic dogs, before and after administration of an oral omega-6/omega-3 fatty acid feed supplement. A pilot study. Veterinary Research Communications 2011: 35: 501-509. Abstract
PubMed ID (PMID): 21786009
Reprint: M. Haftek
Comments: This pilot study provides evidence that supplementing the diet of atopic dogs with an omega-6/omega-3 commercial formulation for two months increased stratum corneum lipids and the coverage of deep intercellular spaces with lipid lamellae. These study is important for the demonstration that orally-administered fatty acids can have a biochemical and morphological effect on the skin barrier. Nevertheless, whether or not such an effect would be associated with any relevant clinical benefit has not yet been proven with certainty.
Comments: This pilot study provides evidence that supplementing the diet of atopic dogs with an omega-6/omega-3 commercial formulation for two months increased stratum corneum lipids and the coverage of deep intercellular spaces with lipid lamellae. These study is important for the demonstration that orally-administered fatty acids can have a biochemical and morphological effect on the skin barrier. Nevertheless, whether or not such an effect would be associated with any relevant clinical benefit has not yet been proven with certainty.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA
