Friday, February 8, 2013

Neurogenic Keratoconjunctivitis Sicca with Ipsilateral Dry Nose

Matheis FL, Walser-Reinhardt, Spiess BM. Canine neurogenic keratoconjunctivitis sicca: 11 cases (2006-2010). Vet Opthalmol 2012; 15: 288-290Abstract. 
PubMed ID (PMID): 22051024
ReprintFL Matheis 
Comments: This short communication is about an uncommon cause of keratoconjunctivitis sicca that is often accompanied by usually unilateral (ipsilateral) dry nose with hyperkeratosis and/or crusting. If nasal lesions are present, damage to the preganglionic parasympathetic fibers proximal to the pterygopalatine ganglion is suspected. Treatment with oral pilocarpine drops appears to yield some benefit. Note: this paper does not provide much detail on nasal lesions, but it explains, in the introduction, the neurologic basis of this syndrome.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA

Pemphigus Variants in Humans


Joly P, Litrowski N. Pemphigus group (vulgaris, vegetans, foliaceus, herpetiformis, brasiliensis). Clin Dermatol 2011; 29: 432-436Abstract. 
PubMed ID (PMID): 21679871
ReprintP Joly 
Comments: This paper is a short review of the epidemiology, clinical signs, histopathology and immunologic characteristics and prognosis of the most common variants of pemphigus in humans. This paper does not cover the treatment options for each disease.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA