Friday, June 30, 2017

A Comprehensive Review on Human Pemphigus

Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS and Amagai M. Pemphigus. Nature Reviews Disease Primers 2017, 3; 17026(Link to PubMed). 
PubMed ID (PMID): 28492232
Reprints: Masayuki Amagai
Comments: These comments will be very short: this is clearly one of the best reviews ever written on this topic: this paper provides detailed information on the pathogenesis, clinical signs, histopathology, immunopathology and treatment of human pemphigus vulgaris and foliaceus; a must read for board examination preparation.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA

Bovine Papillomavirus 14 as a Cause of Feline Sarcoids

Munday JS, Thomson N, Dunowska M, Knight CG, Laurie RE and Hills S. Genomic characterization of the feline sarcoid-associated papillomavirus and proposed classification as Bos taurus papillomavirus type 14. Veterinary Microbiology 2015, 177; 289-295(Link to PubMed). 
PubMed ID (PMID): 2580470
Reprints: John Munday
Comments: Proliferative lesions resembling those of equine sarcoids have been recognized in felids for nearly two decades, and their link to a novel papillomavirus identified as "feline sarcoid-associated papillomavirus - FeSarPV" has been proposed. This paper reveals the genomic sequence of this novel papillomavirus and confirms its homology with other members of the Deltapapillomavirus genus, the bovine papillomavirus (BPV)-1, -2 and -13. The authors propose the name of BPV-14. These results suggest that, in cats as in horses, sarcoids are mesenchymal proliferations caused by cross-species infections with BPVs.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA