Thursday, February 22, 2018

More Than you Ever Wanted to Know about the Cat Flea

Rust MK; The biology and ecology of cat fleas and advancements in their pest management: A Review. Insects 20Oct 27;8: 118(Link to PubMed). 
PubMed ID (PMID): 29366565
Reprints: Open Access
Comments: This is, perhaps, one of the most extensive reviews on this topic. Of particular interest for the residents will be the sections on the flea biology, the diseases of medical and veterinary importance transmitted by this flea, the on-animal treatment studies and the issue of insecticide resistance.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA

IL-31, a Relevant Cytokine for Human (and Canine) Atopic Dermatitis

Bağci IS, Ruzicka T. IL-31: A new key player in dermatology and beyond. Journal of Allergy and Clinical Immunology 2018, ePub ahead of print(Link to PubMed). 
PubMed ID (PMID): 29366565
Reprints:Isin Bagci
Comments: With the usage of drugs that target the IL-31 directly (for example the lokivetmab) or signal transduction by its receptor (e.g. oclacitinib), we would expect residents to be familiar with this pruritogenic cytokine and its receptor. This paper reviews the structure of IL-31 and its receptor, their function and the role of this cytokine in dermatologic and nondermatologic diseases of humans
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA

Comprehensive Review on the Use of Cyclosporine in Dogs

Archer TM, Boothe DM, Langston VC, Fellman CL, Lunsford KV, Mackin AJ. Oral cyclosporine treatment in dogs: a review of the literature. Journal of Veterinary Internal Medicine 2014, 28; 1-20(Link to PubMed). 
PubMed ID (PMID): 24341787
Reprints: Open Access
Comments: This paper, published a few years ago, provides a very thorough review of the pharmacology and therapeutic aspects of cyclosporine therapy in dogs with immunologic diseases. A must read for residents.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA