Thursday, February 22, 2018
IL-31, a Relevant Cytokine for Human (and Canine) Atopic Dermatitis
Bağci IS, Ruzicka T. IL-31: A new key player in dermatology and beyond. Journal of Allergy and Clinical Immunology 2018, ePub ahead of print. (Link to PubMed).
PubMed ID (PMID): 29366565
Comments: With the usage of drugs that target the IL-31 directly (for example the lokivetmab) or signal transduction by its receptor (e.g. oclacitinib), we would expect residents to be familiar with this pruritogenic cytokine and its receptor. This paper reviews the structure of IL-31 and its receptor, their function and the role of this cytokine in dermatologic and nondermatologic diseases of humans