Friday, February 8, 2013

Neurogenic Keratoconjunctivitis Sicca with Ipsilateral Dry Nose

Matheis FL, Walser-Reinhardt, Spiess BM. Canine neurogenic keratoconjunctivitis sicca: 11 cases (2006-2010). Vet Opthalmol 2012; 15: 288-290Abstract. 
PubMed ID (PMID): 22051024
ReprintFL Matheis 
Comments: This short communication is about an uncommon cause of keratoconjunctivitis sicca that is often accompanied by usually unilateral (ipsilateral) dry nose with hyperkeratosis and/or crusting. If nasal lesions are present, damage to the preganglionic parasympathetic fibers proximal to the pterygopalatine ganglion is suspected. Treatment with oral pilocarpine drops appears to yield some benefit. Note: this paper does not provide much detail on nasal lesions, but it explains, in the introduction, the neurologic basis of this syndrome.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA