Irvine AD, McLean IWH, Leung DYM. Filaggrin mutations associated with skin and allergic skin diseases. New England Journal of Medicine 2011; 365: 1315-1327. No Abstract
PubMed ID (PMID): 21991953
Reprint: D. Leung
Comments: This is a nicely written and well illustrated review on the structure of filaggrin, its function and the implications of FLG mutations in the pathogenesis of ichthyosis vulgaris and atopic dermatitis in humans. Don't forget to view the supplementary material, which has an additional beautiful figure.
Recommended by: Thierry Olivry, NC State University, Raleigh, North Carolina, USA
